hrp0089p2-p335 | Pituitary, Neuroendocrinology and Puberty P2 | ESPE2018

The Effect of Polychlorinobiphenyls on Premature Puberty in Girls

Guven Raziye Burcu , Ozen Samim , Gokşen Damla , Korkmaz Ozlem , Darcan Şukran

Introduction: Studies show that onset of puberty in girls is occurring at increasingly younger ages. Environmental endocrine disruptors are implicated in the etiology of early puberty. Polychlorobiphenyls (PCBs) are one of the endocrine disruptor with proven estrogenic effects.Aim: To investigate the effect of PCBs on premature puberty in girls.Materials-Methods: The study group was selected from girls aged 2–8 years with a di...